Parkinson et parkinsonismes

Médicaments

• White matter fractional anisotropy predicts Parkinson's disease medication changes with deep brain stimulation
  Le 28 septembre 2026

  Parkinsonism Relat Disord. 2026 Sep 23;152:108999. doi: 10.1016/j.parkreldis.2026.108999. Online ahead of print. ABSTRACT Diffusion-based tractography has been used to predict deep brain stimulation …

• Exploring the therapeutic potential of Astragalin in Parkinson's disease: a network pharmacology approach
  Le 28 septembre 2026

  Ann Med Surg (Lond). 2026 Jul 29;88(9):5733-5743. doi: 10.1097/MS9.0000000000005442. eCollection 2026 Sep. ABSTRACT BACKGROUND/OBJECTIVES: Parkinson's disease (PD) is a neurodegenerative disorder…

• Effects of an Inpatient Program on Medication Errors in Hospitalized People with Parkinson's Disease
  Le 28 septembre 2026

  Ann Neurol. 2026 Aug 31. doi: 10.1002/ana.78345. Online ahead of print. ABSTRACT OBJECTIVE: Hospitalized people with Parkinson's disease (PwP) face increased risks of medication errors and discharge…

• Cognition endpoints for Parkinson's disease: A roadmap for developing patient-focused assessment tools to accelerate drug development
  Le 28 septembre 2026

  J Parkinsons Dis . 2026 Sep 21:1877718X261483866. doi: 10.1177/1877718X261483866. Online ahead of print. ABSTRACT Cognitive dysfunction is a prevalent and impactful feature of Parkinson's disease (PD…

• Continuous apomorphine infusion modulates cortical hyperexcitability and abnormal plasticity in Parkinson's disease
  Le 28 septembre 2026

  J Parkinsons Dis . 2026 Sep 18:1877718X261479077. doi: 10.1177/1877718X261479077. Online ahead of print. ABSTRACT BackgroundSeveral studies have demonstrated the clinical benefit of apomorphine…

Études cliniques phase 3 et phase 4

• New guidance and public search portal for clinical trials approved in Canada: Notice
  Le 28 septembre 2026

  Our file number: 26-104462-113 July 29, 2026 On this page What we did About the guidance document About the search portal Contact us What we did Health Canada has a new guidance on registering…

• Clinical trials in late-stage Parkinson's disease
  Le 28 septembre 2026

  J Parkinsons Dis . 2026 Sep 22:1877718X261491591. doi: 10.1177/1877718X261491591. Online ahead of print. ABSTRACT Late-stage Parkinson's disease (LSPD) represents an under-recognized and under…

• A pilot phase IIa randomized, placebo-controlled, double-blind trial of intravenous human pluripotent adipose-derived stem cells (PASCs) in Parkinson's disease: The REPOSE study
  Le 28 septembre 2026

  Cell Transplant. 2026 Jan-Dec;35:9636897261492438. doi: 10.1177/09636897261492438. Epub 2026 Sep 23. ABSTRACT Pluripotent adipose-derived stem cells (PASCs) are a non-tumorigenic, stress-enduring…

• OnabotulinumtoxinA for Painful Foot Dystonia in Parkinson Disease: A Randomized, Double-Blind, Placebo-Controlled Trial
  Le 28 septembre 2026

  Neurol Clin Pract. 2026 Dec;16(6):e200659. doi: 10.1212/CPJ.0000000000200659. Epub 2026 Sep 17. ABSTRACT BACKGROUND AND OBJECTIVES: Pain associated with foot dystonia is a common and disabling…

• Early clinical experience with IPX203 in Parkinson's disease with motor fluctuations
  Le 28 septembre 2026

  J Neural Transm (Vienna). 2026 Sep 22. doi: 10.1007/s00702-026-03299-6. Online ahead of print. ABSTRACT Motor fluctuations remain a major challenge in the treatment of Parkinson's disease (PD)…

• Therapeutics candidates and repurposing strategies to target parkinson's disease pathology: current evidence and future directions
  Le 28 septembre 2026

  Metab Brain Dis. 2026 Sep 9;41(1):209. doi: 10.1007/s11011-026-01961-2. ABSTRACT Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder worldwide, affecting over 8.5 million…

Chirurgie

• Moving Beyond the Hyperkinetic Hypothesis for Weight Gain After Deep Brain Stimulation in Parkinson Disease
  Le 28 septembre 2026

  Neuromodulation. 2026 Aug 4:S1094-7159(26)01321-8. doi: 10.1016/j.neurom.2026.07.651. Online ahead of print. ABSTRACT OBJECTIVES: Weight loss is a common manifestation of Parkinson disease (PD) and…

• Pre-operative neural substrates of deep brain stimulation outcomes: A systematic review and cross-disorder network synthesis
  Le 28 septembre 2026

  Neurosci Biobehav Rev. 2026 Sep 17;191:106977. doi: 10.1016/j.neubiorev.2026.106977. Online ahead of print. ABSTRACT BACKGROUND: Deep brain stimulation (DBS) is an established therapy for movement…

• Adaptive versus conventional deep brain stimulation for bradykinesia in Parkinson's disease: a comparative effectiveness analysis
  Le 28 septembre 2026

  Acta Neurol Belg. 2026 Sep 14. doi: 10.1007/s13760-026-03192-9. Online ahead of print. ABSTRACT BACKGROUND: Conventional deep brain stimulation (cDBS) is an established treatment for motor…

• Gamma Knife radiosurgery in patients with indwelling deep brain stimulator systems
  Le 28 septembre 2026

  Br J Neurosurg. 2026 Sep 1:1-6. doi: 10.1080/02688697.2026.2727102. Online ahead of print. ABSTRACT INTRODUCTION: Deep brain stimulation (DBS) is an established therapy for medically intractable…

• Novel predictors of postoperative delirium after awake subthalamic nucleus deep brain stimulation for Parkinson's disease
  Le 28 septembre 2026

  BMJ Neurol Open. 2026 Sep 3;8(2):e001742. doi: 10.1136/bmjno-2026-001742. eCollection 2026. ABSTRACT BACKGROUND: Postoperative delirium (POD) is a common complication of deep brain stimulation (DBS)…

Approches multidisciplinaires

• Clinical efficacy and safety of electroacupuncture at the motor area for Parkinson's disease with musculoskeletal pain: a randomized controlled trial
  Le 28 septembre 2026

  Zhongguo Zhen Jiu. 2026 Sep 12;46(9):1415-1420. doi: 10.13703/j.0255-2930.20250604-k0002. Epub 2026 Jul 6. ABSTRACT OBJECTIVE: To observe the clinical efficacy and safety of electroacupuncture (EA)…

• Stress and Parkinson's disease: from dysfunctional detection to impaired handling: a narrative review
  Le 28 septembre 2026

  J Neural Transm (Vienna). 2026 Sep 24. doi: 10.1007/s00702-026-03267-0. Online ahead of print. ABSTRACT Stress can precipitate Parkinson's disease (PD), and conversely, PD imposes substantial stress…

• Neurogrit Gold Alleviates Motor, Behavioural, and oxidative stress deficits in the MPTP-induced Drosophila melanogaster model of Parkinson's disease
  Le 28 septembre 2026

  Brain Res. 2026 Sep 7:150542. doi: 10.1016/j.brainres.2026.150542. Online ahead of print. ABSTRACT Parkinson's disease is characterized by degeneration of dopaminergic neurons in the midbrain,…

• Dual-Task Exercises for Dynamic Balance, Motor Function, Functional Mobility, and Dual-Tasking in Individuals With Parkinson's Disease: A Meta-Analysis With Meta-Regression
  Le 28 septembre 2026

  Ann Rehabil Med. 2026 Aug;50(4):244-264. doi: 10.5535/arm.260060. Epub 2026 Aug 28. ABSTRACT To evaluate the (1) effectiveness of dual-task (DT) exercise in improving dynamic balance, motor function,…

• Walking to the beat: the impact of non-invasive brain stimulation and music on gait in Parkinson's disease
  Le 28 septembre 2026

  Parkinsonism Relat Disord. 2026 Sep 23;152:108993. doi: 10.1016/j.parkreldis.2026.108993. Online ahead of print. ABSTRACT INTRODUCTION: Walking impairments in Parkinson's disease (PD), including…

Thérapies alternatives

• Effectiveness of mindfulness meditation on balance, cognitive functions, quality of life, and falls prevention in Parkinson's disease: A systematic review
  Le 28 septembre 2026

  Neuropsychol Rehabil. 2026 Sep 7:1-34. doi: 10.1080/09602011.2026.2725697. Online ahead of print. ABSTRACT Scientific interest in mindfulness meditation as complementary therapy for Parkinson's…

• Effects of eccentric upper limbs exercises, added with virtual reality, on tremor and upper limbs function in people with Parkinson's disease: A randomized clinical trial
  Le 28 septembre 2026

  J Hand Ther. 2026 Sep 22:S0894-1130(26)00062-1. doi: 10.1016/j.jht.2026.06.002. Online ahead of print. ABSTRACT BACKGROUND: Parkinson's disease is a progressive neurodegenerative disorder. Eccentric…

• Effects of basic and dual-task training programs on physical function in Parkinson's disease: The PARKEX study
  Le 28 septembre 2026

  PLoS One. 2026 Sep 18;21(9):e0358534. doi: 10.1371/journal.pone.0358534. eCollection 2026. ABSTRACT Exercise is a promising non-pharmacological intervention for motor and non-motor symptoms in…

• Dance as Rehabilitation in Parkinson's Disease: A Scoping Review of Motor, Non-Motor, and Cognitive Outcomes
  Le 28 septembre 2026

  J Dance Med Sci. 2026 Sep 3:1089313X261479319. doi: 10.1177/1089313X261479319. Online ahead of print. ABSTRACT INTRODUCTION: Dance is a multimodal experience, integrating movement and music, with…

• Image-guided programming improves motor control in chronic subthalamic nucleus deep brain stimulation in Parkinson's disease: A prospective study
  Le 28 septembre 2026

  J Parkinsons Dis . 2026 Sep 26:1877718X261492273. doi: 10.1177/1877718X261492273. Online ahead of print. ABSTRACT BackgroundImage-guided programming (IGP) enables optimization and personalization of…

• Comparative Effectiveness of Cognitive Behavioral Therapy Delivery Formats on Anxiety, Depression, and Quality of Life in Parkinson's Disease: A Network Meta-Analysis
  Le 28 septembre 2026

  Am J Geriatr Psychiatry. 2026 Aug 16:S1064-7481(26)00502-6. doi: 10.1016/j.jagp.2026.08.015. Online ahead of print. ABSTRACT BACKGROUND: Anxiety and depression are common in Parkinson's disease (PD),…

• Supporting Medication Adherence in Parkinson's Through Education: A Scoping Review of Interventions
  Le 28 septembre 2026

  Health Expect. 2026 Oct;29(5):e70852. doi: 10.1111/hex.70852. ABSTRACT BACKGROUND: Medication adherence in Parkinson's is complex, time-sensitive, and influenced by clinical, behavioural, and…

• Effects of deep brain stimulation on functional autonomy and quality of life in Parkinson's disease: A systematic review and meta-analysis
  Le 28 septembre 2026

  J Parkinsons Dis. 2026 Sep 21:1877718X261461967. doi: 10.1177/1877718X261461967. Online ahead of print. ABSTRACT BackgroundDeep brain stimulation (DBS) of the subthalamic nucleus (STN) is an…

• User Experience and Satisfaction With a Web-Based Application to Improve Intelligibility in Parkinson's Disease
  Le 28 septembre 2026

  Int J Lang Commun Disord. 2026 Nov-Dec;61(6):e70344. doi: 10.1111/1460-6984.70344. ABSTRACT BACKGROUND/OBJECTIVES: Motor speech impairments, such as hypokinetic dysarthria, are highly prevalent among…

• Why do some patients adhere worse? The role of frailty and depression in Parkinson disease
  Le 28 septembre 2026

  Patient Educ Couns. 2026 Nov;152:109823. doi: 10.1016/j.pec.2026.109823. Epub 2026 Aug 17. ABSTRACT OBJECTIVE: To investigate associations of frailty, depression, disease severity, and…

• Wearable Sensors in Gait Assessment for Parkinson Disease and Stroke in Real-World Environments: Systematic Review and Meta-Analysis
  Le 28 septembre 2026

  J Med Internet Res. 2026 Sep 25;28:e93413. doi: 10.2196/93413. ABSTRACT BACKGROUND: Real-world gait assessment has gained momentum in populations with walking impairments, offering insights beyond…

• Multifunctional polyaniline@Cu(0.95)V(2)O(5)@carbon cloth composite for zinc ion battery-powered wearable sensing system toward Parkinson's auxiliary diagnosis
  Le 28 septembre 2026

  J Colloid Interface Sci. 2026 Sep 11;727:141578. doi: 10.1016/j.jcis.2026.141578. Online ahead of print. ABSTRACT Flexible electronic technology is rapidly advancing toward intelligence, self…

• Moving beyond monitoring: wearable technology (PKG) for the diagnosis of Parkinson's disease
  Le 28 septembre 2026

  BMJ Neurol Open. 2026 Sep 3;8(2):e001689. doi: 10.1136/bmjno-2026-001689. eCollection 2026. ABSTRACT BACKGROUND: The use of wearable technology results in objective and reliable monitoring of motor…

• Smartphone-Based Multimodal Digital Biomarker Integration for Parkinson's Disease Screening and Diagnostic Support
  Le 28 septembre 2026

  Neurol Ther. 2026 Sep 1. doi: 10.1007/s40120-026-01023-w. Online ahead of print. ABSTRACT INTRODUCTION: Timely identification of Parkinson's disease (PD) is often delayed because of clinical…

• Better Conversations With Parkinson's: Feasibility and Acceptability of a Novel Communication Partner Training Telehealth Intervention
  Le 26 août 2026

  Int J Lang Commun Disord. 2026 Sep-Oct;61(5):e70308. doi: 10.1111/1460-6984.70308. ABSTRACT BACKGROUND: Communication Partner Training (CPT) has an established evidence base in aphasia, dementia and…

Québec

• 🔵🟢 CRiNQUÉ arrive bientôt !
  Le 28 septembre 2026

  🔵🟢 CRiNQUÉ arrive bientôt ! 🟠🟡 Conçue avec notre communauté et développée en collaboration avec nos partenaires régionaux, CRiNQUÉ est une plateforme d’activités physiques en ligne accessible en tout…

• Les Cafés Art-Science sont de retour !
  Le 28 septembre 2026

  Les Cafés Art-Science sont de retour ! 🎨🔬 Découvrez les plus récentes avancées en recherche sur la maladie de Parkinson et échangez autour de ces sujets à travers des activités artistiques…

• Comment les facteurs génétiques déterminent le parcours et l'évolution de la maladie de Parkinson
  Le 28 septembre 2026

  👉 Disponible en rediffusion ! Pourquoi la maladie de Parkinson évolue-t-elle différemment d’une personne à l’autre ? Découvrez le rôle de la génétique, les tests disponibles au Québec et les avancées…

• 🚨 Plus de cours en ligne depuis un an ?
  Le 28 septembre 2026

  🚨 Plus de cours en ligne depuis un an ? Ce n'est pas un hasard ! On avait une bonne raison... 😏 Avec CRiNQUÉ, nous avons choisi d'offrir une formule plus souple, plus diversifiée et adaptée à votre…

• Saviez-vous que le célèbre chef français Paul Bocuse a vécu près d'une décennie avec la maladie de Parkinson ?
  Le 28 septembre 2026

  Saviez-vous que le célèbre chef français Paul Bocuse a vécu près d'une décennie avec la maladie de Parkinson ? Le 22 octobre prochain, le Ritz-Carlton Montréal accueillera une soirée gastronomique…

• 🧠 Contribuez à mieux comprendre la peur du mouvement
  Le 28 septembre 2026

  🧠 Contribuez à mieux comprendre la peur du mouvement Saviez-vous que la peur de bouger ou de faire de l'activité physique peut avoir un impact important sur le quotidien de certaines personnes vivant…

• Photos from Parkinson Québec's post
  Le 28 septembre 2026

  💬 RUBRIQUE SCIENTIFIQUE - SEPTEMBRE 2026 Quels sont les besoins, les barrières et les stratégies de communication liés à la maladie de Parkinson ? Comment ces enjeux diffèrent-ils selon les contextes…

• (English follow)
  Le 28 septembre 2026

  (English follow) 🎥 Parkinson Québec recherche des adolescents ou jeunes adultes à l’aise en anglais pour témoigner dans une courte vidéo et partager leur expérience de vie avec la maladie de…

Canada

• Lancez votre assurance : Parkinson Canada s’associe à Spotify
  Le 28 septembre 2026

  Un rythme bien à soi Chacun bouge à son propre rythme. Cette idée est au cœur de Trouvez votre assurance, la campagne continue de Parkinson Canada visant à redéfinir la façon dont les personnes…

• The Neuroscience of Nostalgia: What Happens When We Look Back
  Le 28 septembre 2026

  By Iman V. Photo by Laris Larsswa on Unsplash. As you drive home from a long day at work, the radio starts playing another song from its regular list. Perhaps thousands of people are listening to the…

• Un simple test sanguin pourrait-il accélérer le diagnostic de la maladie de Parkinson ?
  Le 26 août 2026

  Principaux points à retenir Le diagnostic du Parkinson repose actuellement uniquement sur l’observation clinique – il n’existe toujours pas de test sanguin, et aucun test à lui seul ne peut confirmer…

États-Unis

• Dyskinesia
  Le 28 septembre 2026

  Dyskinesia refers to involuntary, uncontrolled movements that can affect the face, arms, legs, or trunk. They can look fluid or dance-like, although they may also appear as jerking movements or…

• Special Edition: “Ask the Physical Therapist” with Teresa Baker
  Le 28 septembre 2026

  Special Edition: “Ask the Physical Therapist” with Teresa Baker Special guest expert! October is National Physical Therapy Month and to commemorate the month and to spotlight the important role…

• Parkinson’s Perspectives: Musicians with Parkinson’s
  Le 28 septembre 2026

  Perspectives from People with Parkinson’s At the American Parkinson Disease Association (APDA), we know that some of the most powerful insights about Parkinson’s disease (PD) come from the people…

• The Different Medications of Parkinson’s Explained
  Le 28 septembre 2026

  Smart Patients Blog Series 2 of 5: Dr. Gilbert Discusses Parkinson’s Disease Medications This article is part 2 in our Smart Patients Blog Series Parkinson’s disease (PD) medications continue to…

• A Parkinson’s diagnosis can raise big questions in a family: Was there a genetic link that contributed to developing the disease...
  Le 28 septembre 2026

  A Parkinson’s diagnosis can raise big questions in a family: Was there a genetic link that contributed to developing the disease? How should other family members think about their risk? Should people…

• Virtual reality gait training shows lasting mobility gains in Parkinson’s
  Le 28 septembre 2026

  Both aquatic Tai Chi and virtual reality (VR) training improved walking, balance, mobility, and gait symmetry in people with Parkinson’s disease . However, VR training led to greater improvements in…

• In Parkinson’s, most dance studies focus on movement over mind
  Le 28 septembre 2026

  Dance-based programs for people with Parkinson’s disease have primarily focused on the effects of such interventions on motor problems, with nonmotor symptoms and cognitive changes receiving…

• New AI data set aims to advance remote Parkinson’s diagnosis
  Le 28 septembre 2026

  A team of U.S. scientists has compiled a large data set of remotely collected data from people with and without Parkinson’s disease , which the scientists hope will serve as an important tool for…

• Approved Parkinson’s treatment wins OK in EU, to be sold as Hopledo
  Le 28 septembre 2026

  Hopledo (IPX203), an extended-release formulation of levodopa and carbidopa sold as Crexont in the U.S., has now won approval in the European Union as a treatment for adults with Parkinson’s disease…

• Blood gene signature predicts risks of Parkinson’s complications
  Le 28 septembre 2026

  A score derived from gene activity measured in blood samples can predict a higher risk of developing cognitive impairment and gait freezing in people with Parkinson’s disease , according to a study…

International

• Cost of Parkinson’s: study shows medical expenses, people having to step out of the workforce, and informal caregiving costs Europe nearly €23bn a year
  Le 28 septembre 2026

  The socioeconomic cost of Parkinson’s across Europe is estimated to be €22.8 billion a year, according to a new study. This equates to a mean cost of €14,278 per person living with the condition, or…

• New Parkinson’s films and TV shows for autumn 2026 and beyond
  Le 28 septembre 2026

  A host of new films and documentaries coming out this autumn are set to help raise awareness of Parkinson’s, showing a range of people and fictional characters living with the condition. Recent hit…