DVM, PhD, FCAHS
CHUM Research Centre
Administrative technician : Joëlle Casamajou
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Director of research
Department of medicine, University of Montreal
Canada research chair in diabetes and pancreatic beta-cell function
Canadian academy of health sciences
Department of medicine, McGill University
Journal of biological chemistry editorial board
Diabetes editorial board
Type 2 diabetes, Islet of Langerhans, Beta cell, Insulin, Glucose homeostasis.
Our research program focuses on the regulation of pancreatic beta-cell function and its dysregulation in type 2 diabetes. Our goal is to understand how the beta-cell responds to changes in its metabolic environment, in particular the impact of chronically elevated levels of glucose and fatty acids on insulin secretion, insulin gene expression, and beta-cell replication. In addition, we are exploring the role of nutrient-sensing G Protein-Coupled Receptors (GPCRs) and Regulators of G protein Signaling (RGS proteins) in pancreatic islet function and glucose homeostasis.