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Physician Interventional cardiology, CHUM

Full professor Department of medicine, Université de Montréal

Research Interests

  • Investigation of the influence of different risks factors (aging, cigarette smoking, diabetes, hypercholesterolemia) on neovascularization in response to ischemia.
  • Characterization of the influence of physiologic or excessive oxidative stress on ischemia-induced neovascularization.
  • Role of endothelial progenitor cells (EPCs) in postnatal neovascularization in the presence of different risks factors and/or in conditions of increased oxidative stress.
  • Our studies combine in vivo experiments on genetically modified mice, in vitro studies using different cell cultures (primary endothelial cells, HUVECs, EPCs, etc.) and molecular biology experiments. Some of our studies involve gene and/or cell therapies.


Metabolic diseases, including obesity and diabetes, are major risk factors for the development of several chronic diseases, including cardiovascular diseases, and are the leading causes of mortality and morbidity in Western countries. The research components of this multidisciplinary axis foc…

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