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Director of research and innovation CHUM

Scientific director CRCHUM

Full professor Department of medicine, Université de Montréal

Other Affiliations

Associate Editor Diabetologia

Fellow Canadian academy of health sciences

Member Journal of biological chemistry editorial board Diabetes editorial board

Adjunct Professor Department of medicine, McGill University

Research Interests

Our research program focuses on the regulation of pancreatic beta-cell function and its dysregulation in type 2 diabetes. Our goal is to understand how the beta-cell responds to changes in its metabolic environment, in particular the impact of chronically elevated levels of glucose and fatty acids on insulin secretion, insulin gene expression, and beta-cell replication. In addition, we are exploring the role of nutrient-sensing G Protein-Coupled Receptors (GPCRs) and Regulators of G protein Signaling (RGS proteins) in pancreatic islet function and glucose homeostasis.


Metabolic diseases, including obesity and diabetes, are major risk factors for the development of several chronic diseases, including cardiovascular diseases, and are the leading causes of mortality and morbidity in Western countries. The research components of this multidisciplinary axis foc…

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