Radiochemistry and cyclotron
Our highly specialized team has the expertise to produce radiopharmaceuticals for Positron Emission Tomography (PET) imaging studies involving diagnosis, follow-up and better understanding of diseases.
For instance, the fluorine-18 (18F) can be incorporated into a fatty acid derivative, 14(R,S)-[18F]fluoro-6-thia-heptadecanoic acid ([18F]FTHA), which accumulates in tissues with abnormal fatty acid metabolism, and thus can be useful in identifying disturbances in fat metabolism in specific tissues/ organs.
Our team works in the implementation of existing radiotracers for clinical research. We are also conducting several innovative research projects developing new promising radiolabeled molecules to improve the detection, to monitor treatment efficacy and to better understand the progression of diseases such as cancer, diabetes, neurodegenerative and cardiovascular diseases. This non-invasive imaging technology allows a fast and efficient translation of important findings from the fundamental research to the clinic via preclinical research.
The production of these radiotracers is performed in GMP environment. More importantly, automated modules in shielded hot cells, including two cells equipped with telemanipulator robotic arms enable the synthesis and manipulation of these radiotracers without any exposure of the Radiochemistry and Cyclotron personnel to radioactivity. Moreover, the distribution of these radiotracers to the injection room, either at the CRCHUM animal facility or at the new CHUM nuclear medicine facility for injections to patients, is greatly facilitated by a pneumatic system, which quickly delivers the radiotracers in less than a minute.
Our services are available to researchers from universities, hospitals and for projects in partnership with the industry.
Alejandro Hernandez Saiz
Research Officer & Delegate Health Physics
Research Officer & Quality Control Specialist
Luis Michel Alonso Martinez
Research Officer & R&D Specialist
Abdelkader El Amri
Quality Assurance Officer