Radiochemistry and cyclotron

Our team specializes in the production of radioactive isotopes and their incorporation into molecules to produce radiotracers used in medical imaging (positron emission tomography or PET) for diagnostics, but also to monitor diseases over time.

For example, il is possible to incorporate Fluor-18 (¹⁸F) into a fatty acid derivative, 14(R,S)— [¹⁸F] fluoro-6-thia-heptadecanoic acid ([¹⁸F]FTHA), which can accumulate abnormally in tissues demonstrating altered fatty acid metabolism.  

This highly specialized team is conducting several research projects to develop existing radiotracers as well as new molecules. Our work allows us to improve disease detection and treatment monitoring and to better understand the progression of illnesses such as cancers, diabetes, or neurodegenerative and cardiovascular disorders. This translational research combines basic research with clinical practice.  

The core production of these radiotracers is done in an environment of good manufacturing practice (GMP). We use automated modules inside shielded cells, including two cells equipped with robotic arms to handle radioactivity without exposing personnel. 

The distribution of radiotracers to the CRCHUM animal facility and to the nuclear medicine department is carried out by a rapid pneumatic transport system that delivers products in a few minutes.  

Our services are available for researchers in the academic, hospital and industrial sectors.