The research focuses on integrating nephrogenomics and precision medicine into the management of adult kidney diseases. It addresses the contribution and clinical implications of genetic testing, as well as patient experiences and the associated ethical issues. A central focus is the application of genomics in kidney transplantation, particularly to guide therapeutic decisions, assess living donors, and optimize the care pathway. The research also examines thrombotic microangiopathies and complement-mediated diseases, aiming to improve etiological diagnosis, risk stratification, and understanding of underlying pathophysiological mechanisms.