Dt. P., Ph.D.
CHUM Research Centre
Department of nutrition, Université de Montréal
514 890-8000, ext. 30847
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Program biomedical sciences - Graduate studies, Université de Montréal
Hepatic encephalopathy, liver disease, liver failure, mitochondrial disease, lactic acidosis, Leigh syndrome French Canadian version, malnutrition, brain, liver, mitochondrial dysfunction, inflammation, oxidative stress, molecular biology, imaging, animal models, basic studies, clinical studies.
In general, my research activities concern pathologies affecting the brain and the liver, and are basic and clinical in nature. Specifically, my laboratory is interested in:
- Implication of nutritional factors related to liver disease's complications including hepatic encephalopathy and the prevention of malnutrition in chronic liver disease.
- Analysis of factors and mechanisms related to the triggering of lactic acidosis crisis in children afflicted with French Canadian Leigh Syndrome.
- Study of the impact of gene mutation (LRPPRC) on mitochondrial function and susceptibility to inflammatory stress, in vitro and in vivo.
- Study of the relation between oxidative stress, inflammation and brain function as well as antioxidant interventions in order to reduce reactive species toxicity and inflammatory modulators