The Research Center of the Center hospitalier de l'Université de Montréal (CRCHUM) is the largest research center in biomedical sciences and health care at the University of Montreal, and among the largest in Canada. Situated at a few steps, with an underground tunnel from the Champs de Mars metro station, the CRCHUM offers a dynamic and innovative work environment in ultramodern facilities at the cutting edge of technology.  

Cancer research theme

The Cancer research theme is situated on the 10^th floor of the CRCHUM, wherein multiple collaborative projects take place amongst teams focusing on different cancer types and innovative approaches. 

Job Description

Under the supervision of Dr. Saima Hassan, the research assistant will work in her translational research laboratory in breast cancer. Dr. Hassan’s research projects aim to better understand the efficacy of PARP inhibitors, either as single agents or in combination, in breast cancer cell lines, in mice models, or in tissue models derived from breast cancer patients.  The overarching objective is to identify strategic PARPi combinations and which patient population will respond the best to PARP inhibition using a 63-gene signature.  One specific task for the research assistant will be to advance the patient-derived organoid modeling, and to lead the prediction of response to immunotherapy and PARPi project.  

Responsibilities

• Skills in molecular biology techniques, including cell culture, immunohistochemistry, immunofluorescence, flow cytometry, western blots, mice handling (including surgeries for tumor implantations and drug treatments), RNA/DNA extraction, single-cell RNA-seq, CRISPR 
• Skills in lab management tasks  
• Data analysis and project management 
• Will help to teach techniques to graduate and undergraduate students within lab 
• Writing ethics protocols, abstracts, posters/presentations for conferences, and manuscripts in English 
• Collaborative and respectful of lab members, dynamic, efficient, honest and professional 
• Flexible, concerned about getting the job well done, independent, attentive to detail, very organized.  

Qualifications

• Should have completed either an MSc or PhD 
• Should have background in cancer research 
• Should have a minimum of one first-authored publication 
• Good knowledge of oral and written French and English 

Job status

• Flexibility of schedule and work from home possible 
• Salary according to CRCHUM policies 
• Full-time position, 35 hours per week, daytime from Monday to Friday (with occasional weekends) 
• Flexibility of the schedule and work from home possible 
• Non-unionized position 
• Pension plan (RREGOP) from the first day of employment 
• Group insurance 
• Position starts AS SOON AS POSSIBLE, 1-year contract, renewable 
• 20 days of vacation per year after one year 
• 13 statutory holidays 
• 9.6 cash-convertible sick days 
• Salary and benefits according to CRCHUM policies 

The CRCHUM invites women, Aboriginals, visible minorities, ethnic minorities and people with disabilities to apply. The CRCHUM adopts a broad and inclusive definition of diversity that goes beyond applicable laws. The CRCHUM thus encourages all people, regardless of their characteristics, to apply. In accordance with Canadian immigration requirements, please note that priority will be given to Canadian citizens and permanent resident.