Finzi, Andrés

Ph.D.

Principal scientist

CHUM Research Centre

Research theme

Associate professor
Department of microbiology, infectiology and immunology, Université de Montréal

Chairholder
Canada Research Chair on Retroviral Entry

Contact

andres.finzi@umontreal.ca
514-890-8000, ext. 35264

> sentinellecovidquebec.ca

The patient who needs immediate assistance should not communicate directly with the researcher. Instead, they should call the doctor’s office or take other appropriate measures, such as going to the nearest emergency service.

Keywords

HIV-1, envelope glycoproteins, gp120, gp41, fusion, CD4, CXCR4, CCR5, CD4-linked conformation, inhibitors.

Research interests

Prevention of HIV transmission requires approaches that interrupt the early phase of infection with this retrovirus. An event of this phase is the entry of HIV into the target cells, which involves interactions between the envelope glycoproteins (gp120-gp41) and the CD4 receptor as well as the CCR5 or CXCR4 coreceptors. To interrupt viral entry, one must first understand the conformational and structural changes that allow HIV envelope glycoproteins to interact with these receptors to fuse with host cells.

My work is aimed at developing a new class of HIV entry inhibitors as well as designing better HIV immunogens that could pave the way for the development of effective HIV vaccines as well as better treatment options.

Publications

PubMed

News

An old molecule to fight SARS-CoV-2

COVID-19: Nathalie Grandvaux and Andrés Finzi Receive $1.8M from the CFI and the Government of Quebec

HIV research: Nicolas Chomont and Andrés Finzi funded by the NIH

A 3rd Dose of the COVID-19 Vaccine Could be Required for Certain Immunocompromised Individuals

A brand new cocktail to fight HIV

COVID-19: not all antibodies are equal in fighting the virus

Andrés Finzi elected member of the Royal Society of Canada

COVID-19: the number of antibodies neutralizing the virus decreases after six weeks

Combattre le coronavirus avec du plasma convalescent? Andrés Finzi et son équipe dans la bataille (In French only)

La course contre la montre pour la mise au point d’un vaccin (In French only)

La combinaison d’un mimétique moléculaire de CD4 avec un vaccin prévient l’infection par le VIH (In French only)

Andrés Finzi wins the Joe Doupe 2019 Award

Chaires de recherche du Canada : trois nouvelles et deux renouvelées au CRCHUM (In French only)

Curing HIV: four extraordinary experts

New imaging reveals previously unseen vulnerabilities of HIV