Small animal phenotyping and imaging

The SKYSCAN 1176 is a high performance in vivo micro-CT scanner for preclinical research. The large format 11 megapixel x-ray camera gives an unrivalled combination of resolution, image field size and scan speed - everything that is required in a busy and demanding biomedical research laboratory.

Image field width up to 68 mm allows full body mouse and rat scanning. Selectable image resolutions of 9, 18 and 35 µm are available. Variable x-ray applied voltage and filters provide scanning flexibility to allow imaging of a wide range of samples from lung tissue to bone with titanium implants.

The full range of SKYSCAN software is available, including fast volumetric reconstruction, software for 2D / 3D quantitative analysis and for realistic 3D visualization.

The IVIS Spectrum system is an in vivo imaging system that combines 2D optical imaging with 3D optical or tomographic imaging.

The system enables animals to be imaged non-invasively using fluorescence or bioluminescence, enabling longitudinal assessment of disease progression.

DEXA from Scintica is a Dual Energy X-Ray Absorptiometry imager that enables rapid and non-invasive measurements of body composition and other parameters :

• Bone Mineral Content (BMC)
• Bone Mineral Density (BMD)
• Fat and Lean Mass
• Quantitative skeletal measurements
• Etc.

The Promethion Core metabolic cage system enables up to 12 mice to be housed in a temperature- and light-controlled environment on a short-, medium- or long-term basis in a home cage type environment. These housing cages are compatible with the use of environmental enrichment and bedding, minimising the stress and artefactual heat losses associated with housing in a litter free environment. Among other things, the system measures:

• Respiratory quotient: Determines the substrate oxidized by mice
• O2 consumption/CO2 production
• Energy expenditure
• Locomotor activity
• Food (chow) and water consumption
• Continuous mouse weight
• Body temperature (probe implantation required)
• Sleep rate

The CLAMS metabolic cage system enables up to 12 mice to be housed in a temperature- and light-controlled environment on a short or medium-term basis. Among other things, the system measures:

• Respiratory quotient: Determines the substrate oxidized by mice
• O₂ consumption/CO₂ production
• Energy expenditure 
• Locomotor activity
• Food (chow) and water consumption
• Continuous mouse weight
• Body temperature (probe implantation required)
• Sleep rate