The IVIS SpectrumCT in vivo imaging system, the ideal tool for characterizing disease progression

Ideal for longitudinal studies, the IVIS SpectrumCT in vivo preclinical imaging system provides research teams with excellent insights into complex biological systems by enabling simultaneous non-invasive molecular and anatomical imaging in animal models.
IVIS SpectrumCT is an integrative platform that combines the full suite of IVIS optical capabilities, including spectral unmixing, quantitative 2D and 3D bioluminescence and fluorescence with fast, low-dose CT imaging.
IVIS SpectrumCT enables longitudinal workflows to characterize disease progression and therapeutic effect throughout the entire experimental period with quantitative and optical reconstructions.
Improved imaging performance
Fast imaging and the ability to image multiple animals simultaneously while maintaining an average dose per scan of around 13 mGy provide the throughput required (scan and reconstruction times of less than one minute) to rapidly analyze large cohorts of animals and draw robust conclusions from experimental data.
The constant horizontal movement of the gantry and the flat-panel detector offer unrivalled performance for low-dose imaging and automated optical and microCT integration. The rotating animal table rotates 360° to acquire full 3D data. Optical and microCT modalities can also operate independently.
The simple user interface and advanced automated co-registration, visualization and analysis tools are driven by Revvity’s market-leading Living Image software.
Key features include:
- Integrated optical and microCT technology
- 3D optical tomography for fluorescence and bioluminescence
- The industry’s most sensitive detection technology ideal for: bioluminescence, multispectral fluorescence and spectral unmixing
- Cerenkov imaging for optical radiotracer imaging
- Low dose and ultra-fast microCT
- DyCE dynamic enhanced imaging for real time distribution studies of both fluorochromes or PET tracers ideal for PK/PD applications
Author: Junzheng Peng, Core Facilities’ Echo committee
Any questions?
Contact the Small Animal Phenotyping and Imaging core facility team
The IVIS SpectrumCT in vivo imaging system, the ideal tool for characterizing disease progression
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The Core Facilities’ Echo