The research carried out in our laboratory aims to understand how healthy oocytes and embryos develop. We are particularly interested in knowing why and how defects in chromosome segregation can cause infertility. We specialize in the use of new microscopy techniques for the analysis of oocytes and embryos ex-vivo. Our lab projects include: Analysis of spindle-microtubule dynamics in oocytes. Assessing changes in spindle function in relation to maternal age and how errors in chromosome segregation may result. Analysis of the mechanism of chromosome segregation in the embryo and the causes of segregation errors. Analysis of apoptotic pathways between oocytes and embryos.