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Alexandre PRAT


Principal scientistNeuroscience
Alexandre PRAT


The patient who needs immediate assistance should not communicate directly with the researcher. Instead, they should call the doctor’s office or take other appropriate measures, such as going to the nearest emergency service.


Director Neuroimmunology research laboratory, CRCHUM

Physician Division of neurology, CHUM

Full professor Department of neurosciences, Université de Montréal

Adjunct professor Department of immunology, infectiology and microbiology, Université de Montréal

Research Chairs

Chairholder Chaire Power Corporation du Canada en neurosciences de l'Université de Montréal / Power Corporation of Canada Chair in neurosciences, Université de Montréal

Chairholder Chaire de recherche du Canada sur la sclérose en plaque / Canada Research Chair in Multiple Sclerosis

Research Interests

  • The immunological roles of the blood-brain barrier (BBB) in multiple sclerosis, the mechanisms of monocyte and lymphocyte migration across endothelial barriers, and the physiological regulation of endothelial barrier functions by glial cells. 
  • TH17 lymphocyte subsets and biology: novel regulatory pathways and their regulation during inflammation. Novel tight junction molecules of the human BBB. 
  • Novel adhesion molecules of the human BBB.


The mission of the Neuroscience research theme is to elucidate the biological, environmental and social mechanisms of neurological diseases and to develop novel and innovative therapies to prevent, treat or cure them. The research activities are grouped into five themes, incorporating clinica…

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Femme qui regarde au microscope