Phénotypage de rongeurs – cardiovasculaire


La plateforme de phénotypage de rongeurs – cardiométabolique a contribué à la publication des articles scientifiques ci-dessous.

1. Deng AY, Menard A, Deng DW. Shifting Paradigm from Gene Expressions to Pathways Reveals Physiological Mechanisms in Blood Pressure Control in Causation. Int J Mol Sci. 2023 Jan 9; 24(2):1262. doi: 10.3390/ijms24021262. (Telemetry)

2. Bouyakdan K, Manceau R, Robb JL, Rodaros D, Fulton S, Alquier T. Role of astroglial ACBP in energy metabolism flexibility and feeding responses to metabolic challenges in male mice. J Neuroendocrinol. 2022 Dec; 34(12):e13218. (EchoMRI)

3. Claire GerkinsRoy HajjarManon OlieroManuela M Santos. Assessment of Gut Barrier Integrity in Mice Using Fluorescein-Isothiocyanate-Labeled Dextran. J Vis Exp2022 Nov 18;(189). (Optix-MX2)

4. Mohamed N Abdelnabi Manuel Flores Molina Geneviève Soucy Vincent Quoc-Huy Trinh Nathalie Bédard Sabrina Mazouz Nathalie Jouvet Jessica Dion Sarah Tran Marc Bilodeau Jennifer L Estall Naglaa H Shoukry Sex-Dependent Hepatoprotective Role of IL-22 Receptor Signaling in Non-Alcoholic Fatty Liver Disease-Related Fibrosis. Cell Mol Gastroenterol Hepatol2022; 14(6):1269-1294. Epub 2022 Aug 13. (EchoMRI)

5. Lan S, Yang B, Migneault F, Turgeon J, Bourgault M, Dieudé M, Cardinal H, Hickey MJ, Patey N, Hébert MJ. Caspase-3-dependent peritubular capillary dysfunction is pivotal for the transition from acute to chronic kidney disease after acute ischemia-reperfusion injury. Am J Physiol Renal Physiol. 2021 Sep 1; 321(3):F335-F351. (skyscan1176)

6. Touani FK, Borie M, Azzi F, Trudel D, Noiseux N, Der Sarkissian S, Lerouge S. Pharmacological Preconditioning Improves the Viability and Proangiogenic Paracrine Function of Hydrogel-Encapsulated Mesenchymal Stromal Cells. Stem Cells Int. 2021 Jul 28; 2021:6663467. (Optix-MX2)

7. Roberto Diaz-MarinSergio Crespo-GarciaAriel M WilsonManuel BuscarletAgnieszka DejdaFrédérik FournierRachel JuneauThierry AlquierPrzemyslaw Sapieha. Myeloid-resident neuropilin-1 influences brown adipose tissue in obesity. Sci Rep. 2021 Aug 3;11(1):15767. (EchoMRI)

8. Grygorczyk R, Boudreault F, Ponomarchuk O, Tan JJ, Furuya K, Goldgewicht J, Kenfack FD, Yu F. Lytic Release of Cellular ATP: Physiological Relevance and Therapeutic Applications. Life (Basel). 2021 Jul 16; 11(7):700. (Optix-MX2)

9. Croze ML, Guillaume A, Ethier M, Fergusson G, Tremblay C, Campbell SA, Maachi H, Ghislain J, Poitout V.
Combined Deletion of Free Fatty-Acid Receptors 1 and 4 Minimally Impacts Glucose Homeostasis in Mice. Endocrinology. 2021 Mar 1; 162(3):bqab002. (EchoMRI)

10. Ouhaddi Y, Najar M, Paré F, Lussier B, Urade Y, Benderdour M, Pelletier JP, Martel-Pelletier J, Fahmi H. L-PGDS deficiency accelerated the development of naturally occurring age-related osteoarthritis. Aging (Albany NY). 2020 Dec 23;12(24):24778-24797. (skyscan1176)

11. Diallo K, Dussault S, Noll C, Lopez AF, Rivard A, Carpentier AC, Lim GE. 14-3-3ζ mediates an alternative, non-thermogenic mechanism in male mice to reduce heat loss and improve cold tolerance. Mol Metab. 2020 Nov; 41:101052. (EchoMRI)

12. Amate M, Goldgewicht J, Sellamuthu B, Stagg J, Yu FTH. The effect of ultrasound pulse length on microbubble cavitation induced antibody accumulation and distribution in a mouse model of breast cancer. Nanotheranostics. 2020 Sep 15; 4(4):256-269. (Optix-MX2)

13. Najar M, Ouhaddi Y, Paré F, Lussier B, Urade Y, Kapoor M, Pelletier JP, Martel-Pelletier J, Benderdour M, Fahmi H. Arthritis Rheumatol. Role of Lipocalin-Type Prostaglandin D Synthase in Experimental Osteoarthritis. 2020 Sep; 72(9):1524-1533. (skyscan1176)

14. Deng AY, Ménard A. Conserved mammalian modularity of quantitative trait loci revealed human functional orthologs in blood pressure control. PLoS One. 2020 Jul 23; 15(7):e0235756. (Telemetry)

15. Deng AY. Modularity/non-cumulativity of quantitative trait loci on blood pressure. J Hum Hypertens. 2020 Jun; 34(6):432-439. (Telemetry)

16. Deng AY, Ménard A. Functional Captures of Multiple Human Quantitative Trait Loci Regulating Blood Pressure with the Use of Orthologs in Genetically Defined Rat Models.  Can J Cardiol. 2020 May; 36(5):756-763. (Telemetry)

17. Deng AY, Ménard A. Biological convergence of three human and animal model quantitative trait loci for blood pressure. J Hypertens. 2020 Feb; 38(2):322-331. (Telemetry)

18. Paré F, Tardif G, Fahmi H, Ouhaddi Y, Pelletier JP, Martel-Pelletier J. In vivo protective effect of adipsin-deficiency on spontaneous knee osteoarthritis in aging mice. Aging (Albany NY). 2020 Feb 1; 12(3):2880-2896. (skyscan1176)

19. Deng AY, Huot-Marchard JÉ, deBlois D, Thorin E, Chauvet C, Menard A. Functional Dosage of Muscarinic Cholinergic Receptor 3 Signalling, Not the Gene Dose, Determines Its Hypertension Pathogenesis. Can J Cardiol. 2019 May; 35(5):661-670. (Telemetry)

20. Bouyakdan K, Martin H, Liénard F, Budry L, Taib B, Rodaros D, Chrétien C, Biron É, Husson Z, Cota D, Pénicaud L, Fulton S, Fioramonti X, Alquier T. The gliotransmitter ACBP controls feeding and energy homeostasis via the melanocortin system. J Clin Invest. 2019 Apr 2; 129(6):2417-2430. (EchoMRI)

21. Deng AY, deBlois D, Laporte SA, Gelinas D, Tardif JC, Thorin E, Shi Y, Raignault A, Ménard A. Novel Pathogenesis of Hypertension and Diastolic Dysfunction Caused by M3R (Muscarinic Cholinergic 3 Receptor) Signaling. Hypertension. 2018 Sep; 72(3):755-764. (Telemetry)

22. Léa Décarie-SpainSandeep SharmaCécile HryhorczukVictor Issa-GarciaPhilip A BarkerNathalie Arbour Thierry Alquier Stephanie Fulton Nucleus accumbens inflammation mediates anxiodepressive behavior and compulsive sucrose seeking elicited by saturated dietary fat. Mol Metab2018 Apr; 10:1-13. (EchoMRI)

23. Bergeron V, Ghislain J, Vivot K, Tamarina N, Philipson LH, Fielitz J, Poitout V. Deletion of Protein Kinase D1 in Pancreatic β-Cells Impairs Insulin Secretion in High-Fat Diet-Fed Mice. Diabetes. 2018 Jan; 67(1):71-77. (EchoMRI)

24. Ouhaddi Y, Nebbaki SS, Habouri L, Afif H, Lussier B, Kapoor M, Narumiya S, Pelletier JP, Martel-Pelletier J, Benderdour M, Fahmi H. Exacerbation of Aging-Associated and Instability-Induced Murine Osteoarthritis With Deletion of D Prostanoid Receptor 1, a Prostaglandin D2 Receptor. Arthritis Rheumatol. 2017 Sep; 69(9):1784-1795. (skyscan1176)

25. Bosoi CR, Oliveira MM, Ochoa-Sanchez R, Tremblay M, Ten Have GA, Deutz NE, Rose CF, Bemeur C. The bile duct ligated rat: A relevant model to study muscle mass loss in cirrhosis. Metab Brain Dis. 2017 Apr; 32(2):513-518. (EchoMRI)

26. Yang B, Dieudé M, Hamelin K, Hénault-Rondeau M, Patey N, Turgeon J, Lan S, Pomerleau L, Quesnel M, Peng J, Tremblay J, Shi Y, Chan JS, Hébert MJ, Cardinal H.
Anti-LG3 Antibodies Aggravate Renal Ischemia-Reperfusion Injury and Long-Term Renal Allograft Dysfunction. Am J Transplant. 2016 Dec; 16(12):3416-3429. (Renal IR model)

27. Wang Y, Hamet P, Thorin E, Tremblay J, Raelson J, Wu Z, Luo H, Jin W, Lavoie JL, Peng J, Marois-Blanchet FC, Tahir MR, Chalmers J, Woodward M, Harrap S, Qi S, Li CY, Wu J. Reduced blood pressure after smooth muscle EFNB2 deletion and the potential association of EFNB2 mutation with human hypertension risk. Eur J Hum Genet. 2016 Dec; 24(12):1817-1825. (Telemetry)

28. Wang Y, Wu Z, Luo H, Peng J, Raelson J, Ehret GB, Munroe PB, Stoyanova E, Qin Z, Cloutier G, Bradley WE, Wu T, Shen JZ, Hu S, Wu J. The role of GRIP1 and ephrin B3 in blood pressure control and vascular smooth muscle cell contractility. Sci Rep. 2016 Dec 12; 6:38976. (Telemetry)

29. Shamansurova Z, Tan P, Ahmed B, Pepin E, Seda O, Lavoie JL. Adipose tissue (P)RR regulates insulin sensitivity, fat mass and body weight. Mol Metab. 2016 Aug 23;5(10):959-969. (EchoMRI)

30. Crespo K, Ménard A, Deng AY. Retinoblastoma-associated protein 140 as a candidate for a novel etiological gene to hypertension. Clin Exp Hypertens. 2016; 38(6):533-40. doi: 10.3109/10641963.2016.1163373. Epub 2016 Jul 8. (Telemetry)

31. Wang Y, Wu Z, Thorin E, Tremblay J, Lavoie JL, Luo H, Peng J, Qi S, Wu T, Chen F, Shen J, Hu S, Wu J.
Estrogen and testosterone in concert with EFNB3 regulate vascular smooth muscle cell contractility and blood pressure. Am J Physiol Heart Circ Physiol. 2016 Apr 1; 310(7):H861-72. (Telemetry)

32. Deng AY, Chauvet C, Ménard A. Alterations in Fibronectin Type III Domain Containing 1 Protein Gene Are Associated with Hypertension. PLoS One. 2016 Apr 11; 11(4):e0151399. (Telemetry) 

33. Zhao S, Mugabo Y, Ballentine G, Attane C, Iglesias J, Poursharifi P, Zhang D, Nguyen TA, Erb H, Prentki R, Peyot ML, Joly E, Tobin S, Fulton S, Brown JM, Madiraju SR, Prentki M. α/β-Hydrolase Domain 6 Deletion Induces Adipose Browning and Prevents Obesity and Type 2 Diabetes. Cell Rep. 2016 Mar 29;14(12):2872-88. (EchoMRI)

34. Ghislain J, Fontés G, Tremblay C, Kebede MA, Poitout V. Dual-Reporter β-Cell-Specific Male Transgenic Rats for the Analysis of β-Cell Functional Mass and Enrichment by Flow Cytometry. Endocrinology. 2016 Mar;157(3):1299-306. (EchoMRI)

35. Chauvet C, Ménard A, Deng AY. Two candidate genes for two quantitative trait loci epistatically attenuate hypertension in a novel pathway. J Hypertens. 2015 Sep; 33(9):1791-801; discussion 1801. (Telemetry) 

36. Plante E, Menaouar A, Danalache BA, Yip D, Broderick TL, Chiasson JL, Jankowski M, Gutkowska J. Oxytocin treatment prevents the cardiomyopathy observed in obese diabetic male db/db mice. Endocrinology. 2015 Apr; 156(4):1416-28. (Vevo 770)